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Department Faculty

Janice Kiecolt-Glaser

* Jointly with Psychiatry Clinical

Professor Janice Kiecolt-Glaser holds the S. Robert Davis Chair of Medicine in The Ohio State University College of Medicine; she also holds the title of Distinguished University Professor. She is a member of the OSU Institute for Behavioral Medicine Research as well as Professor of Psychiatry and Psychology. Working in the area of psychoneuroimmunology (PNI), she has authored more than 200 articles, chapters, and books, most in collaboration with Dr. Ronald Glaser. Their studies have demonstrated important health consequences of stress, including slower wound healing and impaired vaccine responses; they have also shown that chronic stress substantially accelerates age-related changes in inflammation, linked to some cancers, cardiovascular disease, type II diabetes, osteoporosis, arthritis, and frailty and function decline. In addition, their programmatic work has focused on how personal relationships influence immune and endocrine function, and health. See http://pni.osumc.edu/ for an overview of her research and copies of her publications.

Most notable among her honors is her membership in the Institute of Medicine of the National Academy of Sciences. A Fellow in the American Association for the Advancement of Science, as well as the American Psychological Association, she received the Award for Outstanding Contributions to Health Psychology from Division 38 twice. She is listed in the Institute for Scientific Information ISIHighlyCited.com (among the world's most highly cited authors, a group comprising less than one half of one percent of all publishing researchers). She has served on the editorial boards of 10 journals. Her research has been supported by a series of grants from the National Institutes of Health, including a MERIT award.

Current Research

Although cancer survivors are the primary focus of her current research, her ongoing studies http://www.stressandhealth.org/ also reflect her interests in older adults, marriage, and the interactive influences of stress and dietary intake on immune function. Her current projects are addressing questions such as longer-term mental and physical health of breast cancer survivors, the ability of mind-body interventions such as yoga to modulate endocrine and immune responses, and the role that proinflammatory cytokines play in combination with depression among cancer survivors who experience debilitating fatigue.

Another segment of her current research focuses on the intersection of nutritional neuroscience with psychoneuroimmunology. Drawing on behavioral, nutritional, immunological, and cardiovascular research, two projects address the ways that stress, depression, and obesity interact to enhance responses to meals high in saturated fat, substantially boosting postprandial inflammation and fueling chronic inflammatory and atherogenic responses. One of these studies involves breast cancer survivors and the second involves healthy married couples; for the marriage study, she is also interested in how the couples’ responses to a marital problem discussion may interact with their responses to the meals.

Selected Publications (out of 200+ papers and chapters)

Kiecolt-Glaser JK, Gouin JP, & Hantsoo LV (2010). Close relationships, inflammation, and health. Neuroscience and Biobehavioral Reviews. Close relationships, inflammation, and health. Neuroscience and Biobehavioral Reviews. 35, 33-38. PMC2891342

Kiecolt-Glaser JK (2010). Stress, food, and inflammation: Psychoneuroimmunology and nutrition at the cutting edge. Psychosomatic Medicine, 72, 365-369. PMC2868080

Kiecolt-Glaser JK, Loving TJ, Stowell JR, Malarkey WB, Lemeshow S, Dickinson SL, Glaser R (2005). Hostile marital interactions, proinflammatory cytokine production, and wound healing. Archives of General Psychiatry, 62:1377-1384.

Glaser R, Kiecolt-Glaser JK (2005). Stress-induced immune dysfunction: Implications for health. Nature Reviews Immunology 5:243-251.

Kiecolt-Glaser JK, Preacher KJ, MacCallum RC, Atkinson C, Malarkey WB, Glaser R (2003). Chronic stress and age-related increases in the proinflammatory cytokine interleukin-6. Proceedings of the National Academy of Sciences, USA 100:9090-9095. PMC166443

Glaser R, Robles TF, Malarkey WB, Sheridan JF, Kiecolt-Glaser JK (2003). Mild depressive symptoms are associated with amplified and prolonged inflammatory responses following influenza vaccination in older adults. Archives of General Psychiatry 60:1009-1014.

Kiecolt-Glaser JK, McGuire L, Robles T, Glaser R (2002). Psychoneuroimmunology: Psychological influences on immune function and health. Journal of Consulting and Clinical Psychology 70:537-547.

Kiecolt-Glaser JK, McGuire L, Robles T, Glaser R (2002). Emotions, morbidity, and mortality: New perspectives from psychoneuroimmunology. Annual Review of Psychology 53:83-107.

Kiecolt-Glaser JK, McGuire L, Robles T, Glaser, R (2002). Psychoneuroimmunology and psychosomatic medicine: Back to the future. Psychosomatic Medicine 64:15-28.

Kiecolt-Glaser JK, Newton TL (2001). Marriage and health: His and hers. Psychological Bulletin 127:472-503.

Kiecolt-Glaser JK, Glaser R (1999). Chronic stress and mortality among older adults. Journal of the American Medical Association 282:2259-2260.

Kiecolt-Glaser JK, Page GG, Marucha PT, MacCallum RC, Glaser R (1998). Psychological influences on surgical recovery: Perspectives from psychoneuroimmunology. American Psychologist 53:1209-1218.

Kiecolt-Glaser JK, Glaser R, Gravenstein S, Malarkey WB Sheridan J (1996). Chronic stress alters the immune response to influenza virus vaccine in older adults. Proceedings of the National Academy of Sciences 93:3043-3047. PMC39758



Address

Institute for Behavioral Medicine Research
Ohio State University College of Medicine
460 Medical Center Drive, Room 130C
Columbus, OH 43210-1228
(614) 293-3499
kiecolt-glaser.1@osu.edu